{"id":38340,"date":"2026-07-18T09:26:02","date_gmt":"2026-07-18T06:26:02","guid":{"rendered":"https:\/\/www.merceknet.com\/tr\/?p=38340"},"modified":"2026-07-18T09:26:02","modified_gmt":"2026-07-18T06:26:02","slug":"zayiflama-ignesine-hap-alternatifi-avrupadan-gunluk-semaglutid-tedavisine-onay","status":"publish","type":"post","link":"https:\/\/www.merceknet.com\/tr\/2026\/07\/18\/zayiflama-ignesine-hap-alternatifi-avrupadan-gunluk-semaglutid-tedavisine-onay\/","title":{"rendered":"Zay\u0131flama i\u011fnesine hap alternatifi: Avrupa\u2019dan g\u00fcnl\u00fck semaglutid tedavisine onay"},"content":{"rendered":"

Obezite tedavisinde son y\u0131llarda yayg\u0131nla\u015fan GLP-1 grubu enjeksiyonlar\u0131n ard\u0131ndan tablet formundaki ila\u00e7lar da yeni bir d\u00f6nemin kap\u0131s\u0131n\u0131 aralad\u0131.<\/p>\n

Avrupa Komisyonu, Avrupa \u0130la\u00e7 Ajans\u0131 Be\u015fer\u00ee T\u0131bbi \u00dcr\u00fcnler Komitesinin may\u0131s ay\u0131nda verdi\u011fi olumlu g\u00f6r\u00fc\u015f\u00fcn ard\u0131ndan, semaglutid etken maddeli ve g\u00fcnde bir kez kullan\u0131lan zay\u0131flama hap\u0131na onay verdi. \u0130la\u00e7, Avrupa Birli\u011fi genelinde kilo y\u00f6netimi amac\u0131yla ruhsatland\u0131r\u0131lan ilk a\u011f\u0131zdan kullan\u0131lan GLP-1 resept\u00f6r agonisti olarak kay\u0131tlara ge\u00e7ti.<\/p>\n

Kimler kullanabilecek?<\/h2>\n

Yeni tablet, v\u00fccut kitle indeksi 30 ve \u00fczerinde olan obez yeti\u015fkinler i\u00e7in onayland\u0131.<\/p>\n

V\u00fccut kitle indeksi 27 ile 30 aras\u0131nda bulunan fazla kilolu yeti\u015fkinlerde ise ilac\u0131n kullan\u0131labilmesi i\u00e7in tip 2 diyabet, y\u00fcksek tansiyon, kolesterol bozuklu\u011fu, uyku apnesi veya kalp-damar hastal\u0131\u011f\u0131 gibi kiloyla ba\u011flant\u0131l\u0131 en az bir sa\u011fl\u0131k sorununun bulunmas\u0131 gerekiyor.<\/p>\n

Tedavinin d\u00fc\u015f\u00fck kalorili beslenme program\u0131 ve art\u0131r\u0131lm\u0131\u015f fiziksel aktiviteyle birlikte uygulanmas\u0131 \u00f6ng\u00f6r\u00fcl\u00fcyor. Tablet yaln\u0131zca yeti\u015fkinler i\u00e7in ruhsatland\u0131r\u0131l\u0131rken, re\u00e7eteyle kullan\u0131labilecek.<\/p>\n

\u0130\u011fneyle ayn\u0131 etken maddeyi i\u00e7eriyor<\/h2>\n

Hap ve haftal\u0131k enjeksiyonun etken maddesi semaglutid olarak a\u00e7\u0131kland\u0131. Bu madde, ba\u011f\u0131rsaklarda do\u011fal olarak salg\u0131lanan GLP-1 hormonunun etkisini taklit ediyor.<\/p>\n

GLP-1 ila\u00e7lar\u0131 beynin i\u015ftah ve tokluk merkezlerini etkileyerek a\u00e7l\u0131k hissinin azalmas\u0131na, tokluk s\u00fcresinin uzamas\u0131na ve g\u00fcnl\u00fck enerji al\u0131m\u0131n\u0131n d\u00fc\u015fmesine yard\u0131mc\u0131 oluyor.<\/p>\n

Yeni hap\u0131n onaylanan hedef dozu g\u00fcnl\u00fck 25 miligram olurken, tedaviye daha d\u00fc\u015f\u00fck dozlarla ba\u015flanmas\u0131 i\u00e7in 1,5, 4 ve 9 miligraml\u0131k tablet se\u00e7enekleri de kabul edildi.<\/p>\n

Her g\u00fcn a\u00e7 karn\u0131na al\u0131nacak<\/h2>\n

Tablet formundaki ilac\u0131n haftal\u0131k enjeksiyonlardan en \u00f6nemli farklar\u0131ndan biri kullan\u0131m s\u0131kl\u0131\u011f\u0131 olacak.<\/p>\n

Enjeksiyon haftada bir kez uygulan\u0131rken, tablet g\u00fcnde bir kez kullan\u0131lacak. \u0130lac\u0131n en az sekiz saatlik a\u00e7l\u0131\u011f\u0131n ard\u0131ndan al\u0131nmas\u0131 ve tabletten sonra yemek yemek, i\u00e7ecek t\u00fcketmek veya ba\u015fka bir ila\u00e7 kullanmak i\u00e7in en az 30 dakika beklenmesi gerekiyor.<\/p>\n

Bu kullan\u0131m d\u00fczenine uyulmamas\u0131, ilac\u0131n emilimini ve tedaviden al\u0131nan sonucu etkileyebilece\u011finden doktorun belirledi\u011fi programa ba\u011fl\u0131 kal\u0131nmas\u0131 \u00f6nem ta\u015f\u0131yor.<\/p>\n

Klinik \u00e7al\u0131\u015fmada yakla\u015f\u0131k y\u00fczde 17 kilo kayb\u0131<\/h2>\n

Onaya dayanak olu\u015fturan OASIS 4 \u00e7al\u0131\u015fmas\u0131nda, g\u00fcnde 25 miligram a\u011f\u0131zdan semaglutid kullanan obez veya kiloya ba\u011fl\u0131 ek hastal\u0131\u011f\u0131 bulunan fazla kilolu yeti\u015fkinler incelendi.<\/p>\n

\u00dcretici \u015firketin a\u00e7\u0131klad\u0131\u011f\u0131 sonu\u00e7lara g\u00f6re ya\u015fam tarz\u0131 d\u00fczenlemeleriyle birlikte kullan\u0131lan tablette ortalama kilo kayb\u0131 yakla\u015f\u0131k y\u00fczde 17 olurken, plasebo grubunda bu oran y\u00fczde 3 seviyesinde kald\u0131. \u00c7al\u0131\u015fmaya kat\u0131lanlar\u0131n yakla\u015f\u0131k \u00fc\u00e7te biri v\u00fccut a\u011f\u0131rl\u0131\u011f\u0131n\u0131n y\u00fczde 20\u2019sini veya daha fazlas\u0131n\u0131 kaybetti.<\/p>\n

Bu sonu\u00e7lar her hastan\u0131n ayn\u0131 oranda kilo verece\u011fi anlam\u0131na gelmiyor. Elde edilecek sonu\u00e7; ba\u015flang\u0131\u00e7 kilosuna, beslenme ve egzersiz al\u0131\u015fkanl\u0131klar\u0131na, tedaviye uyuma ve ki\u015fisel sa\u011fl\u0131k \u00f6zelliklerine g\u00f6re de\u011fi\u015febiliyor.<\/p>\n

Zay\u0131flama hap\u0131n\u0131n avantajlar\u0131 neler?<\/h2>\n

Tablet formu, enjeksiyondan \u00e7ekinen veya i\u011fne uygulamas\u0131n\u0131 s\u00fcrd\u00fcrmekte zorlanan ki\u015filer i\u00e7in alternatif olu\u015fturabilecek.<\/p>\n

Hap ve i\u011fnenin kar\u015f\u0131la\u015ft\u0131rmas\u0131<\/h3>\n
\n
\n\n\n\n\n\n\n\n\n\n\n\n
Ba\u015fl\u0131k<\/th>\nG\u00fcnl\u00fck tablet<\/th>\nHaftal\u0131k enjeksiyon<\/th>\n<\/tr>\n<\/thead>\n
Etken madde<\/td>\nSemaglutid<\/td>\nSemaglutid<\/td>\n<\/tr>\n
Kullan\u0131m \u015fekli<\/td>\nA\u011f\u0131zdan<\/td>\nDeri alt\u0131na enjeksiyon<\/td>\n<\/tr>\n
Kullan\u0131m s\u0131kl\u0131\u011f\u0131<\/td>\nG\u00fcnde bir<\/td>\nHaftada bir<\/td>\n<\/tr>\n
Uygulama kolayl\u0131\u011f\u0131<\/td>\n\u0130\u011fne gerektirmez<\/td>\nEnjeksiyon uygulan\u0131r<\/td>\n<\/tr>\n
Kullan\u0131m ko\u015fulu<\/td>\nA\u00e7 karn\u0131na al\u0131nmal\u0131, 30 dakika beklenmeli<\/td>\nBelirlenen haftal\u0131k g\u00fcnde uygulanmal\u0131<\/td>\n<\/tr>\n
Hedef grup<\/td>\nObez veya ek hastal\u0131\u011f\u0131 olan fazla kilolu yeti\u015fkinler<\/td>\nRuhsatland\u0131r\u0131lan ya\u015f ve hasta gruplar\u0131<\/td>\n<\/tr>\n
Re\u00e7ete<\/td>\nZorunlu<\/td>\nZorunlu<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div>\n

\u0130\u011fne kullanmak istemeyen hastalar a\u00e7\u0131s\u0131ndan a\u011f\u0131zdan tedavi daha kabul edilebilir ve s\u00fcrd\u00fcr\u00fclebilir bulunabilir. Avrupa \u0130la\u00e7 Ajans\u0131 da tabletin baz\u0131 hastalar i\u00e7in haftal\u0131k enjeksiyona k\u0131yasla daha uygun bir se\u00e7enek olabilece\u011fini belirtiyor.<\/p>\n

G\u00fcnl\u00fck kullan\u0131m dezavantaj olu\u015fturabilir<\/h2>\n

Hap formunun i\u011fne gerektirmemesi \u00f6nemli bir kolayl\u0131k sa\u011flasa da ilac\u0131n her g\u00fcn belirli kurallara g\u00f6re al\u0131nmas\u0131 gerekiyor.<\/p>\n

En az sekiz saatlik a\u00e7l\u0131k \u015fart\u0131, yaln\u0131zca az miktarda suyla al\u0131nmas\u0131 ve sonras\u0131nda 30 dakika boyunca ba\u015fka bir \u015fey t\u00fcketilmemesi, baz\u0131 hastalarda tedaviye uyumu zorla\u015ft\u0131rabilir.<\/p>\n

Haftal\u0131k enjeksiyonda ise ila\u00e7 yedi g\u00fcnde bir uygulan\u0131yor. Bu nedenle hangi formun daha kolay oldu\u011fu ki\u015finin g\u00fcnl\u00fck ya\u015fam\u0131, al\u0131\u015fkanl\u0131klar\u0131 ve tedaviye uyum \u00f6zelliklerine g\u00f6re de\u011fi\u015febilir.<\/p>\n

Yan etkiler tablet formunda da g\u00f6r\u00fclebilecek<\/h2>\n

\u00dcretici \u015firket, a\u011f\u0131zdan kullan\u0131lan semaglutidin g\u00fcvenlilik ve tolere edilebilirlik profilinin enjeksiyon formuyla genel olarak uyumlu oldu\u011funu a\u00e7\u0131klad\u0131.<\/p>\n

Semaglutid tedavilerinde en s\u0131k bildirilen yan etkiler aras\u0131nda \u015funlar bulunuyor:<\/p>\n

    \n
  • Bulant\u0131 ve kusma<\/li>\n
  • \u0130shal veya kab\u0131zl\u0131k<\/li>\n
  • Kar\u0131n a\u011fr\u0131s\u0131 ve haz\u0131ms\u0131zl\u0131k<\/li>\n
  • Ba\u015f a\u011fr\u0131s\u0131<\/li>\n
  • \u0130\u015ftah azalmas\u0131<\/li>\n<\/ul>\n

    Bu etkiler \u00f6zellikle tedavinin ba\u015flang\u0131c\u0131nda veya doz art\u0131r\u0131l\u0131rken daha belirgin g\u00f6r\u00fclebiliyor. \u0130lac\u0131n dozu, hastan\u0131n verdi\u011fi yan\u0131t ve ya\u015fad\u0131\u011f\u0131 yan etkilere g\u00f6re doktor taraf\u0131ndan kademeli \u015fekilde d\u00fczenleniyor.<\/p>\n

    \u201cLeblebi gibi\u201d kullan\u0131lacak bir \u00fcr\u00fcn de\u011fil<\/h2>\n

    Tablet formuna ge\u00e7ilmesi, ilac\u0131n s\u0131radan veya risksiz bir zay\u0131flama \u00fcr\u00fcn\u00fc oldu\u011fu anlam\u0131na gelmiyor.<\/p>\n

    \u0130la\u00e7 yaln\u0131zca kilo vermek isteyen herkes i\u00e7in geli\u015ftirilmi\u015f kozmetik bir \u00fcr\u00fcn de\u011fil; belirli t\u0131bbi \u00f6l\u00e7\u00fctleri kar\u015f\u0131layan obez veya kiloya ba\u011fl\u0131 sa\u011fl\u0131k sorunu bulunan fazla kilolu yeti\u015fkinlerin tedavisinde kullan\u0131lacak.<\/p>\n

    Doktor de\u011ferlendirmesi yap\u0131lmadan, ba\u015fka bir ki\u015finin ilac\u0131 kullan\u0131larak veya sosyal medya tavsiyeleriyle tedaviye ba\u015flanmas\u0131 ciddi sa\u011fl\u0131k sorunlar\u0131na yol a\u00e7abilir. Doz art\u0131r\u0131m\u0131, yan etkilerin y\u00f6netimi ve tedavinin ne zaman sonland\u0131r\u0131laca\u011f\u0131 mutlaka hekim taraf\u0131ndan belirlenmeli.<\/p>\n

    Kilo verildikten sonra devam tedavisinde kullan\u0131labilir mi?<\/h2>\n

    Tablet formunun, enjeksiyonla kilo veren baz\u0131 hastalarda uzun d\u00f6nem kilo kontrol\u00fc amac\u0131yla de\u011ferlendirilmesi m\u00fcmk\u00fcn olabilir. Ancak enjeksiyondan hapa ge\u00e7i\u015fin kimler i\u00e7in uygun oldu\u011fu ve hangi dozun kullan\u0131laca\u011f\u0131 ki\u015fiye \u00f6zel olarak planlanmal\u0131.<\/p>\n

    Obezite kronik bir hastal\u0131k oldu\u011fu i\u00e7in ila\u00e7 b\u0131rak\u0131ld\u0131ktan sonra i\u015ftah\u0131n yeniden artmas\u0131 ve verilen kilolar\u0131n geri al\u0131nmas\u0131 ihtimali bulunuyor. Kal\u0131c\u0131 sonu\u00e7 i\u00e7in beslenme al\u0131\u015fkanl\u0131klar\u0131n\u0131n de\u011fi\u015ftirilmesi, d\u00fczenli fiziksel aktivite ve uzun d\u00f6nem t\u0131bbi takip gerekiyor.<\/p>\n

    Avrupa onay\u0131 hemen T\u00fcrkiye\u2019de sat\u0131\u015f anlam\u0131na gelmiyor<\/h2>\n

    Avrupa Komisyonunun karar\u0131, ilac\u0131n Avrupa Birli\u011fi \u00fclkelerinde pazarlanabilmesi i\u00e7in d\u00fczenleyici izin sa\u011fl\u0131yor. \u00dcretici \u015firket, tableti 2026\u2019n\u0131n ikinci yar\u0131s\u0131nda daha fazla \u00fclkede kullan\u0131ma sunmay\u0131 planlad\u0131\u011f\u0131n\u0131 a\u00e7\u0131klad\u0131.<\/p>\n

    \u0130lac\u0131n T\u00fcrkiye\u2019de ne zaman sat\u0131\u015fa sunulaca\u011f\u0131, fiyat\u0131 ve geri \u00f6deme kapsam\u0131nda bulunup bulunmayaca\u011f\u0131na ili\u015fkin hen\u00fcz resmi bir a\u00e7\u0131klama yap\u0131lmad\u0131. T\u00fcrkiye\u2019de kullan\u0131labilmesi i\u00e7in ulusal ruhsatland\u0131rma ve ilgili mevzuat s\u00fcre\u00e7lerinin tamamlanmas\u0131 gerekecek.<\/p>\n

    <\/h3>\n","protected":false},"excerpt":{"rendered":"

    Obezite tedavisinde kullan\u0131lan haftal\u0131k zay\u0131flama i\u011fnelerine a\u011f\u0131zdan al\u0131nan yeni bir se\u00e7enek eklendi. Avrupa Komisyonu, semaglutid i\u00e7eren ve g\u00fcnde bir kez kullan\u0131lan tablete kilo y\u00f6netimi amac\u0131yla pazarlama izni verdi. \u0130la\u00e7, Avrupa Birli\u011fi\u2019nde obezite tedavisi i\u00e7in onaylanan ilk a\u011f\u0131zdan kullan\u0131lan GLP-1 se\u00e7ene\u011fi oldu.<\/p>\n","protected":false},"author":6,"featured_media":38341,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[18],"tags":[2847,12836,12740],"class_list":["post-38340","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-saglik","tag-obezite","tag-zayiflama-hapi","tag-zayiflama-igneleri"],"yoast_head":"\nZay\u0131flama i\u011fnesine hap alternatifi: Avrupa\u2019dan g\u00fcnl\u00fck semaglutid tedavisine onay - Merceknet Haber<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.merceknet.com\/tr\/2026\/07\/18\/zayiflama-ignesine-hap-alternatifi-avrupadan-gunluk-semaglutid-tedavisine-onay\/\" \/>\n<meta property=\"og:locale\" content=\"tr_TR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Zay\u0131flama i\u011fnesine hap alternatifi: Avrupa\u2019dan g\u00fcnl\u00fck semaglutid tedavisine onay - Merceknet Haber\" \/>\n<meta property=\"og:description\" content=\"Obezite tedavisinde kullan\u0131lan haftal\u0131k zay\u0131flama i\u011fnelerine a\u011f\u0131zdan al\u0131nan yeni bir se\u00e7enek eklendi. 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